mRNA疫苗 研究:可防胰脏癌复发
(伦敦9日综合电)一款使用信使核糖核酸(mRNA)技术研发的创新疫苗,可以防止部分胰脏癌病人在手术后复发,为治疗胰脏癌带来新希望。专家指这项新发明预示癌症治疗将进入一个新时代。
英国《泰晤士报》报导这项mRNA疫苗新技术,由美国科学家与创制辉瑞新冠肺炎疫苗的德国公司BioNTech共同研发,使用的mRNA技术与研发新冠肺炎疫苗的技术相同。mRNA疫苗为接受肿瘤手术的胰脏癌病人提供新治疗,防止癌细胞复发。大部分癌肿瘤会不受控地扩散,因为人体免疫系统无法认出癌细胞是外来“敌人”,但mRNA可以认出癌细胞表面的突变蛋白质。mRNA疫苗为每名病人度身定造,注射入病人体内后,能训练病人的免疫系统,以白血球T细胞杀死血液中的胰脏癌细胞,防止癌症复发。
接受试验的16名胰脏癌病人,在施手术切除肿瘤后,每人注射八剂mRNA疫苗。其中半数在18个月后没有癌细胞。其余病人对mRNA疫苗没反应,当中有6人死亡或复发。类似的BioNTech疫苗也正在进行治疗大肠癌病人的试验。胰脏癌是死亡率最高的癌症,九成病人在确诊后两年内死亡。英国每年有1万人死于胰脏癌。

文:综合报导
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