◤全球大流行◢ 应对新变种保护力 次世代疫苗加强剂更强
（华盛顿23日综合电）美国一项真实世界研究显示，更新版新冠肺炎疫苗加强剂可增强先前已打过多达4剂旧版疫苗的人对新变种病毒株的保护力。
这项发布在美国疾病防治中心（CDC）《发病率和死亡率周报》（Morbidity and Mortality Weekly Report）、涵盖超过36万人的研究提供了第一手证据，证明辉瑞BNT（Pfizer-BioNTech）和莫德纳（Moderna）研制的新冠肺炎更新版疫苗提供比原版疫苗更好的保护力。
自9月推出以来，包含原始病毒株和奥密克戎（Omicron）亚变种BA.4、BA.5的次世代疫苗加强剂为18至49岁群体提供了比老年人更大的益处。
研究表明，当接种间隔时间为8个月或以上时，与原版疫苗相比，次世代疫苗加强剂的相对疫苗效力在18至49岁群体中为56%，在50至64岁群体中为48%，在65岁级以上群体中为43%。
当接种加强剂的间隔时间为2至3个月时，疫苗效力的变化较小，在28%至31%的范围内。
然而，研究作者警告，参与研究者可能不记得他们的疫苗接种状态、过去感染史和慢性病医疗状况，且大众对双价加强剂的接受度低，这些因素都可能使研究结果产生偏差。
根据美国政府数据，截至目前，已接种约3500万剂更新版疫苗加强剂，约占总人口的10%。
研究作者也警告，该研究可能无法推广至未来出现的新变种病毒株，因为主要流行的病毒株不断变化。
过去2个月，奥密克戎亚变种BQ.1和BQ.1.1已取代BA.5成为美国主要流行的病毒株。而辉瑞和莫德纳推出的次世代疫苗便是以BA.5为基础做改良。
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